Assisted Living Community Measures (v2026A)
Posted: 08/04/2025

Release Notes:
Data Element
Version 2026A

Name:Off-Label Antipsychotic Drug Prescribed
Collected For: ALC-01
Definition:Off-label use of antipsychotic drugs.
Question:Has the resident been prescribed an antipsychotic for off-label use?
Format:
Length:1
Type:Alphanumeric
Occurs:1
Allowable Values:

Y (Yes) The resident been prescribed an antipsychotic for off-label use.

N (No) The resident has not been prescribed an antipsychotic listed for off-label use.
Notes for Abstraction:FDA Approved Uses for antipsychotics are listed in the table below. Select yes when the resident is prescribed an antipsychotic for purposes other than those described in the table below.
  • Select yes if the antipsychotic is prescribed as a PRN.
  • Example: resident given haldol for aggressive behavior, select ‘Yes’.

Antipsychotics Table
Conventional Antipsyhcotics (Generic Name) FDA Approved Uses
Haldol (Haloperidol) Schizophrenia (PO, IM, IV), Tourette's Disorder (oral)
Loxitane/Adusave (Loxapine) Schizophrenia (PO), Acute treatment of agitation associated with schizophrenia or Bipolar I Disorder (inhalation)
Navane (Thiothixene) Schizophrenia (PO)
Orap (Pimozide) Tourette’s Disorder (PO)
Thorazine (Chlorpromazine) Bipolar Disorder (PO), Schizophrenia (PO), Severe & acute agitation/aggression associated with psychiatric disorders (IM), Prolonged or Intractable Hiccups (PO, IM, IV), Nausea/Vomiting (PO, IM, IV), Presurgical apprehension (PO, IM)
Prolixin/Permitil (Fluphenazine) Psychotic Disorders (PO, IM, SQ)
Compro (Prochlorperazine) Acute nausea/vomiting (PO, IM, IV, rectal), General Anxiety Disorder (PO), Schizophrenia (PO)
Mellaril (Thioridazine) Schizophrenia (PO)
Stelazine (Trifluoperazine) Schizophrenia (PO)
Trilafon (Perphenazine) Nausea/Vomiting (PO), Schizophrenia (PO)
Triavil (Perphenazine and Amitriptyline) Major Depressive Disorder and Anxiety (PO), Schizophrenia with depressive symptoms (PO)
Moban (Molindone) Schizophrenia (PO)

Atypical Antipsychotics (Generic Name) FDA Approved Uses
Abilify/Abilify Asimtufii/Abilify Maintena/Abilify MyCite (Aripiprazole) Schizophrenia (PO, IM), Bipolar Disorder acute mania/acute episodes with mixed features/maintenance treatment (PO, IM), Treatment-resistant Major Depressive Disorder (PO)
Aristada/Aristada Initio (Aripiprazole Lauroxil) Schizophrenia (IM)
Saphris/Secuado (Asenapine) Schizophrenia (SL, patch), Bipolar Disorder (SL)
Clozaril/Fazaclo/Versacloz (Clozapine) Schizophrenia (PO), Suicidal behavior in schizophrenia/schizoaffective disorder (PO)
Fanapt (Iloperidon) Schizophrenia (PO), Bipolar Disorder (PO)
Zyprexa/Zyprexa Relprevv/Zyprexa Zydis (Olanzapine) Schizophrenia (PO, IM), Bipolar Disorder acute mania/acute episodes with mixed features/maintenance treatment (PO), Acute Bipolar major depression as adjunctive with Fluoxetine (PO), Treatment-resistant Major Depressive Disorder (unipolar) as adjunctive to Fluoxetine (PO), Severe/Acute Agitation/Aggression associated with psychiatric disorders (IM)
Symbyax (Olanzapine and Fluoxetine) Acute Bipolar Disorder depressive episode (PO) , Treatment Resistant Depression (PO)
Lybalvi (Olanzapine and Samidorphan) Bipolar I Disorder acute mania and acute episodes with mixed features (PO), Schizophrenia (PO)
Invega/Invega Hafyera/Invega Trinza/Invega Sustenna (Paliperidone) Schizophrenia (PO, IM), Schizoaffective Disorder (PO, IM)
Seroquel (Quetiapine) Seroquel/Seroquel XR (Quetiapine) Schizophrenia (PO), Bipolar Disorder acute mania/acute episodes with mixed features/major depression monotherapy/maintenance monotherapy (PO), Major Depressive Disorder (PO)
Risperdal/Risperda Consta/Perseris/Uzedy (Risperidone) Schizophrenia (PO, IM, SQ), Bipolar Disorder acute mania/acute episodes with mixed features/maintenance (PO, IM)
Geodon (Ziprasidone) Schizophrenia (PO), Bipolar Disorder acute manic episodes with or without mixed features/maintenance as adjunctive to antimanic therapy (PO), Severe/Acute Agitation/Aggression associated with schizophrenia (IM)
Nuplazid (Pimavanserin) Parkinson disease psychosis (PO)
Rexulti (Brexpiprazole) Major Depressive Disorder (PO), Schizophrenia (PO), Agitation associated with dementia due to Alzheimer disease (PO)
Caplyta (Lumateperone) Bipolar Disorder (PO), Schizophrenia (PO)
Vraylar (Cariprazine) Bipolar Disorder (PO), Major Depressive Disorder (PO), Schizophrenia (PO)
Latuda (Lurasidone) Acute depressive episode associated with bipolar without mixed features (PO), Schizophrenia (PO)
Cobenfy (Xanomeline and Trospium Chloride) Schizophrenia (PO)
Suggested Data Sources:
Additional Notes:
Guidelines for Abstraction:
Inclusion Exclusion
None None

Off-Label Antipsychotic Drug Prescribed
Assisted Living Community Measures (v2026A)
Applicable 01-01-26 (1Q26) through 06-30-2026 (2Q26)

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